Fenbendazole for Humans- Dosages, Cancer, safety & Beyond

Fenbendazole for Humans

Even though Fenbendazole for Humans is a widely tested drug in veterinary medicine, we have lately seen many studies that state its anticancer use in humans.

It has been used in dogs, cats and other type of livestock to treat parasitic infections and it has been proved to be widely successful in treating this situation. The drug Fenbendazole works by destroying the cellular structure of parasites and that makes them becoming apoptotic.

There is a widespread record of safety of Fenbendazole for animal use when it comes to difficult parasite infections from several identified parasites. However, lately we have seen many clinical trials that include Fenbendazole to the treatment of several types of tumor initially in animals and then in humans.

There are some anecdotal reports about Fenbendazole and its action over the tumor cells. The theory suggests that Fenbendazole interacts with the mitochondria inside the tumor cells and makes them stop their functioning.

At this point the tumor cells remain without energy and they lead to death which makes humans healthy again. There is no evidence that Fenbendazole acts on healthy human cells and that is why the new clinical trials for Human cancer include this substance as the primary endpoint.

Fenbendazole belongs to a group of medicines that are approved for parasitic infections in humans like menbendazole and albendazole They act the same way and this supports the theory that Fenbendazole is a promising and quite safe substance when it comes to parasitic infections.

Is Fenbendazole Safe for Humans

There are some preliminary clinical trials that support Ivermectin and Fenbendazole as a safe agent for humans suffering from several tumors. We all now the drugs menbendazole and albendazole as two antiparasitic agents that are approved for human use. Fenbendazole belongs to the same group of drastic agents like these substances and that implies that it is also safe for human use.

Additionally, when you have no other option for tumor treatment it would be a good idea to start using Fenbendazole as the agent to stop the multiplication and function of tumor cells. The drug is quite active in disrupting the metabolism of tumor cells.

For that reason theories support that Fenbendazole remains one of the most impressive drugs to reduce the tumor expansion and gradually kill the cancer cells to ensure a full treatment for people who suffer from this life-threatening disease.

Oral Fenbendazole for Cancer Therapy in Humans 

Oral Fenbendazole is one of the most active and widely available drugs for cancer therapy even when it is in experimental phase. There are some promising mechanisms of action for Fenbendazole 444 mg that have to do with the dissolution of the cancer cells.

This happens only in vitro that means in trials that happen in laboratories outside of the human body. When drug-resistant cancer cells are added in the solution the Fenbendazole can easily help in dissolving their cellular structure and eventually make them apoptotic.

Additionally there are some evidence that suggest Fenbendazole remains one of the main drugs that disrupt the cell metabolism in tumor cells. It can interfere in the glucose uptake of these cells and deprive them from energy that is so important when they want to multiply themselves.

As a result the addition of Fenbendazole to the in vitro solution remains a strong agent that reduces the number of cancer cells. Further studies in humans are to be conducted after the FDA has approved Fenbendazole for human use officially.

It is good to know that Fenbendazole remains widely non-soluble in water. That supports the theory that oral Fenbendazole can be packed in tabs and have a wider bioavailability in humans.

Systemic availability of Fenbendazole remains largely a stake for scientists since the creation of stomach diluted tabs will increase the drug action within the human body and make it a lot more drastic for tumor cell reduction.

Fenbendazole cancer clinical trials

As the drug Fenbendazole for Cancer lacks FDA approval there are no official clinical trials for cancer right now for humans. However, there are some preclinical data for cancer cell lines in vitro and in animal models.

There is the hypothesis that Fenbendazole acts in cancer cells by destroying the microtubules, thus making it impossible for them to divide and inhibit their metabolism. Moreover, there are some case reports and anecdotal reports from patients who have been self-administering Fenbendazole when they were to their final stage of cancer.

These reports show that these patients have had a quite impressive progress in cancer treatment, relenting the expansion of the tumor to other organs, and even having complete treatment from this illness.

On the other hand, drugs that belong to the same team as Fenbendazole (Menbendazole and Albendazole) have been included in official clinical trials for certain cancers. The types of cancers studied where gliomas and brain tumors all of them having to do with the central nervous system.

There are some promising results from these trials showing that Fenbendazole could be potentially one of the next blockbusters for cancer treatment in humans.

What does fenbendazole do to the human body

As we all know Fenbendazole is not yet approved by the FDA for human use not for cancer treatment or parasitic infections. However, there is enough evidence to know what Fenbendazole does to the cells of primates, humans included:

🔸 It targets a protein in the cell structure and membrane called beta-tubulin. That anchoring of Fenbendazole with this protein stops the creation of microtubules that are important for the inner skeleton of cells. As a result, the cells cannot operate right and they cannot even divide so they remain inactive and gradually die.

🔸 One of the main anticancer activities of Fenbendazole in humans has to do with the intracellular metabolism of glucose. The drug binds firmly with glucose transporting proteins like GLUT1 and the enzyme hexokinase.

🔸 There is also another activity of Fenbendazole that has to do with the p53 protein. That protein is one of the main ones that suppress the division of tumors.

🔸 Finally one of the main actions of Fenbendazole in the tumor cells has to do with the oxidative stress. The drug can easily increase the concentration of reactive oxygen species in the tumor cells to lead to great damage and final apoptosis of these cells.

Fenbendazole remains one of the premium drug factors for cell division inhibition. That means it can act in tumor cells and make them collapse from the inside, being one of the most promising treatments for cancer after the FDA will approve it for human use.

Fenbendazole dosage for humans with cancer

As there are no official data for Fenbendazole and the doses for cancer in humans, we will give only the case reports and anecdotal reports that have to do with treatment of tumors in humans. The drug is administered by mouth and the initial dose comes to 222mg to 1000mg per day.

The frequency of Fenbendazole intake was once daily. Most patients followed a cycle of 3 consecutive days of Fenbendazole intake followed by a small break of 4 days to ensure there are no side effects from the drug.

It is also good to know that Fenbendazole was taken as a part of a holistic therapy including supplements like Vitamin E, CBD oil and curcumin to ensure the anti-tumor effect of the drug.

However, only a registered oncologist would be liable to give you the exact concentration and dosage for each individual suffering from cancer and wanting to take Fenbendazole as a first line treatment.

Fenbendazole dosage by weight adults

The dosages schemes per kilogram have been studied for Fenbendazole in animals only. However, there are some anecdotal reports for cancer patients taking Fenbendazole as their first line treatment. For an average adult weight 70kg the dosage of Fenbendazole would be close to 3.2mg/kg.

People who suffer from cancer and have a lower body mass index (BMI) could cut this dose to half (1.6mg/kg) and see the results of the drug after two months when they will perform their next PT-SCAN to check the proliferation of cancer in their body.

However, there is no official index of body weight and suggested dosage for Fenbendazole when taken by humans suffering from cancer and in need to treat and dissolve the expansion of tumors in their bodies.